According to numerous studies, the Klotho protein seems to have a positive effect on the body. For example, it may contribute to heart health and cardiovascular maintenance. Considering that various CVDs caused 32 percent of all worldwide deaths in 2019, this could provide optimism to patients.

Klotho Research Findings

The Klotho gene seems to have an influence on the way the body metabolizes energy. It also might reduce inflammation that otherwise appears as redness, swelling or burning sensations. Changes in Klotho protein levels also seem to correlate with alterations of calcium salt deposits (calcification) in veins and constricted blood vessels (endothelial dysfunction).

Additional Klotho Research Details

  • How detected: Medical practitioners can use blood or urine tests to detect Klotho presence in the body. It’s also found in the brain and spinal cord fluid.
  • Where found: Places where most present in the body are the kidney and the brain. Klotho also is found in the parathyroid glands, which are located in the neck behind the thyroid glands.
  • Role played: It regulates calcium and phosphates, which relates to how the body processes Vitamin D. As a result, Klotho maintains the bones and could prevent kidney failure.
  • FGF23 binding: The fibroblast growth factor-23 hormone found in the bones provides the basis behind controlling phosphate and Vitamin D activities. It’s part of what keeps the kidneys functioning the way they should, but it also can affect other areas of the body including the heart, veins and arteries, and it also affects the respiratory system.
  • Phosphate wasting prevention: Proper Klotho functioning and amounts could prevent preliminary symptoms such as frequent urination or declining phosphate levels that relate to a variety of health conditions, not just kidney issues.

Discoveries of positive effects that the Klotho FGF23 binder has on the cardiovascular system could be game-changing. It also could regulate oxygen functioning (promote oxidative stress reduction) that pertains not only to heart but also respiratory health.