Aging brings all sorts of problems no matter how well people take care of their bodies. Part of the reason why is the decline of the Klotho gene present in our bodies with every year that passes.

A primary concern arising includes how declines of Klothos have on the kidneys, but it also could cause oxidative stress, memory or cognitive malfunctions, and other issues. A greater understanding of Klotho’s functioning could change future health treatment.

What is Klotho?

The “Klotho” enzyme, which medical professionals usually detect in the kidneys or the cerebral-spinal area using urine or blood tests, is a protein. It provides a variety of functions, such as regulating calcium and phosphate levels. As a result, it also guides the way vitamin D works in the body, causing this nutrient to metabolize the way it should.

Since 1997, research evidence has revealed Klotho anti-aging effects that can slow down kidney failure progression, reduce oxidative stress levels, and combat memory loss or cognitive disability. Certain laboratory tests on rats demonstrate how this gene also might prevent bone deterioration.

Potential Klotho Treatment Effects

The Klotho gene seems to correlate with kidney functioning, and it might delay chronic kidney disease progression if used for renal failure treatment. This possibility came up after research results detected Klotho decline in urine in people diagnosed with Stage 1 or Stage 2 CKD, which reveals the opposite of what would happen if people did not have a Klotho protein deficiency.

Apparently, a link to bone density in postmenopausal women and Klotho also exists. The KL-VS variant also seems to provide Alzheimer’s patients a way to combat learning and memory issues according to Gladstone Institutes. UC San Francisco researchers also contributed to this research, during which they observed how increased cell receptor activity improved memory capacity.