The Role of Klotho in Chronic Kidney Disease

The Role of Klotho in Chronic Kidney Disease

With approximately 37 million Americans, which is more than one in seven adults, suffering the effects of long-term chronic kidney disease, researchers have turned their attention to the role played by the Klotho protein in chronic kidney disease.  Over the past two...
Klotho Early Biomarker for Chronic Kidney Disease

Klotho Early Biomarker for Chronic Kidney Disease

Klotho is defined as a transmembrane protein that is detected mainly in the brain and kidneys. Klotho is also expressed in kidney distal convoluted tubules and parathyroid cells, and it mediates the role of FGF-23 (a protein that is encoded by the FGF23 gene) in...
Klotho-Choroid Plexus Interaction and Aging

Klotho-Choroid Plexus Interaction and Aging

In understanding the interaction between the aging process and the breakdown of essential proteins that keep our bodies healthy and youthful, it is helpful to review the interconnectedness of our brains, bodies, and critical protein production. The klotho-choroid...